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Article

Extracellular signal-regulated kinase 1 interacts with and phosphorylates CdGAP at an important regulatory site.

Molecular and cellular biology - 1 Aug 2005

Tcherkezian Joseph, Danek Eric I, Jenna Sarah, Triki Ibtissem, Lamarche-Vane Nathalie

Abstract excerpt

Rho GTPases regulate multiple cellular processes affecting both cell proliferation and cytoskeletal dynamics. Their cycling between inactive GDP- and active GTP-bound states is tightly regulated by guanine nucleotide exchange factors and GTPase-activating proteins (GAPs). We have previously identified CdGAP (for Cdc42 GTPase-activating protein) as a specific GAP for Rac1 and Cdc42. CdGAP consists of an N-terminal...

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Identifiers

PMID: 16024771
DOI: 10.1128/MCB.25.15.6314-6329.2005
PMCID: PMC1190322

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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