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Article

Anti-inflammatory nuclear receptor superfamily in multiple sclerosis patients from Sardinia and Sweden.

Neurobiology of disease - 1 Dec 2005

Liu Xuan, Steffensen Knut R, Sanna Alessandra, Arru Giannina, Fois Maria Laura, Rosati Giulio, Sotgiu Stefano, Link Hans, Gustafsson Jan-Ake, Huang Yu-Min

Abstract excerpt

Several nuclear hormone receptors have been associated with inflammatory reactions. Particularly, liver X receptors (LXRs) have recently been identified as key transcriptional regulators of genes involved in lipid homeostasis and inflammation. LXRs are negative regulators of macrophage inflammatory gene expression. Multiple sclerosis (MS), a demyelinating disease of the central nervous system of unknown cause, is...

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Identifiers

PMID: 16023861
DOI: 10.1016/j.nbd.2005.06.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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