Article

Determinants of Scavenger Receptor Expression Levels in Human Macrophages

2021-09-29

Abstract excerpt

<title>Abstract</title> <p>Background Atherosclerosis involves the accumulation of oxidized low-density lipoprotein (OxLDL)-laden foam cells (FC) within the blood vessel intima. Macrophages are transformed to FCs by the uptake of OxLDL, a process mediated by scavenger receptors (SRs), which include MSR1, CD36 and CD68. Atherosclerosis differs in prevalence across ethnic groups, being less common in African than...

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Literature Corpus work: 2f6a25e3-3c6b-5096-961f-fe72731248ae
DOI: 10.21203/rs.3.rs-927119/v1

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