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Article

Regulation of gene expression associated with acute experimental autoimmune encephalomyelitis by Lovastatin

18 May 2004

Abstract excerpt

The attenuation of experimental autoimmune encephalomyelitis (EAE) by Lovastatin (LOV) has now been well established. The present study was designed to explore the global effect of LOV treatment on expression of immune-related genes in lumbar spinal cord (LSC) during acute EAE by using Affymetrix DNA microarrays. LOV treatment demonstrated the limited infiltration of inflammatory cells into the LSC, and...

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PMID: 15197739
DOI: 10.1002/jnr.20130

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