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Article

RAR-related orphan receptor A (RORA): A new susceptibility gene for multiple sclerosis.

Journal of the neurological sciences - 15 Oct 2016

Eftekharian Mohammad Mahdi, Noroozi Rezvan, Sayad Arezou, Sarrafzadeh Shaghayegh, Toghi Mehdi, Azimi Tahereh, Komaki Alireza, Mazdeh Mehrdokht, Inoko Hidetoshi, Taheri Mohammad, Mirfakhraie Reza

Abstract excerpt

Retinoic acid receptor-related orphan receptor alpha (RORA) is proposed to promote Th17 cells differentiation that play a crucial role in many inflammatory diseases, including multiple sclerosis (MS). The gene is also involved in regulation of inflammatory responses and neuronal cell development. The aim of the present study is to determine if any relation exists between RORA rs11639084 and rs4774388 gene...

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Identifiers

PMID: 27653902
DOI: 10.1016/j.jns.2016.08.045

Genes

RORA

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