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Article

Hypomorphic mutation in hnRNP U results in post-implantation lethality.

Transgenic research - 1 Apr 2005

Roshon Michael J, Ruley H Earl

Abstract excerpt

The present study characterized an embryonic lethal mutation induced by insertion of the U3Neo gene trap retrovirus into an intron of the gene encoding heterogeneous ribonuclear protein U (Hnrnpu), which maps to the distal arm of mouse chromosome 1. Murine hnRNP U was found to be identical to the human protein at all but one of 341 amino acid residues. Embryos homozygous for the provirus showed obvious...

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Identifiers

PMID: 16022389
DOI: 10.1007/s11248-004-8147-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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