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Article

Mutation in hotfoot-4J mice results in retention of delta2 glutamate receptors in ER.

The European journal of neuroscience - 1 Oct 2002

Matsuda Shinji, Yuzaki Michisuke

Abstract excerpt

The orphan glutamate receptor delta2 is selectively expressed in Purkinje cells and plays a critical role in cerebellar function. Recently, the ataxia of hotfoot-4J (ho-4J) mice was shown to be caused by a 170-amino acid deletion in the N-terminal region of delta2 receptors. To understand delta2 receptor function, we characterized these mutant receptors (delta2ho) in Purkinje cells. Immunohistochemical staining...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 12405964
DOI: 10.1046/j.1460-9568.2002.02219.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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