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Article

Association of T-cell regulatory gene polymorphisms with susceptibility to gastric mucosa-associated lymphoid tissue lymphoma.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 20 Jul 2006

Cheng Tsu-Yao, Lin Jaw-Town, Chen Li-Tzong, Shun Chia-Tung, Wang Hsiu-Po, Lin Ming-Tsang, Wang Tsang-En, Cheng Ann-Lii, Wu Ming-Shiang

Abstract excerpt

PURPOSE: Helicobacter pylori infection and host susceptibility interact to develop gastric mucosa-associated lymphoid tissue (MALT) lymphoma, and activation of specific T cells might play a crucial role in this process. Recent investigations show that the CTLA4, CD28, and ICOS genes are located on chromosome 2q33 and their polymorphisms confer susceptibility to infectious and immune diseases through deregulation...

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Topics

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Share to Antigens, Differentiation
Share to Antigens, Differentiation, T-Lymphocyte

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CD28 Antigens

Share to CTLA-4 Antigen

Share to Helicobacter Infections

Share to Helicobacter pylori

Share to Inducible T-Cell Co-Stimulator Protein

Share to Lymphoma, B-Cell, Marginal Zone

Source

Identifiers

PMID: 16849765
DOI: 10.1200/JCO.2005.05.5434

Genes

CTLA4
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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