Article
Role of the STK15 Phe31Ile polymorphism in renal cell carcinoma.
Oncology reports - 1 Jan 2007
Hammerschmied Christine G, Stoehr Robert, Walter Bernhard, Wieland Wolf F, Hartmann Arndt, Blaszyk Hagen, Denzinger Stefan
Abstract excerpt
The search of inherited cancer susceptibility factors is an important subject in cancer epidemiology. Analyses of single nucleotide polymorphisms (SNP) in various genes revealed a correlation between the presence of specific allelic variants and cancer predisposition in diverse malignancies. STK15 is an important protein in control of the integrity of the mitotic spindle apparatus and genomic stability. We...
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