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Article

Genomic screens for genes upregulated by demethylation in colorectal cancer: possible usefulness for clinical application.

International journal of oncology - 1 Aug 2005

Ogawa Kazuhiko, Utsunomiya Tohru, Mimori Koshi, Yamashita Keishi, Okamoto Masahiro, Tanaka Fumiaki, Inoue Hiroshi, Ikeda Yoichi, Saku Motonori, Murayama Sadayuki, Mori Masaki

Abstract excerpt

Inactivation of tumor suppressor genes may result in clinically aggressive tumors and poor prognoses for cancer patients. This study was conducted to investigate the clinical significance of genomic screens for genes upregulated by demethylation in colorectal cancer. We performed a comprehensive survey of commonly inactivated genes in colorectal cancer through the functional reactivation of epigenetically...

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PMID: 16010423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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