The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro.

doi:10.1002/j.1460-2075.1992.tb05265.x

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Article

The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro.

The EMBO journal - 1 Jun 1992

te Heesen S, Janetzky B, Lehle L, Aebi M

Abstract excerpt

Asparagine-linked N-glycosylation is a highly conserved and functionally important modification of proteins in eukaryotic cells. The central step in this process is a cotranslational transfer of lipid-linked core oligosaccharides to selected Asn-X-Ser/Thr-sequences of nascent polypeptide chains, catalysed by the enzyme N-oligosaccharyl transferase. In this report we show that the essential yeast protein WBP1 (te...

Topics

Alleles
Amino Acid Sequence
Aspartic Acid Endopeptidases
Base Sequence
Carboxypeptidases
Cathepsin A
Fungal Proteins
Galactosidases
Genes, Fungal
Glycosylation
Hexosyltransferases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Membrane Proteins

Microsomes

Molecular Sequence Data

Oligodeoxyribonucleotides

Plasmids

Promoter Regions, Genetic

Recombinant Fusion Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 1600939
DOI: 10.1002/j.1460-2075.1992.tb05265.x
PMCID: PMC556673

Genes

WBP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1600939-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The yeast WBP1 is essential for oligosaccharyl transferase activity in vivo and in vitro.PMID 1600939Read ↗

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The oligosaccharyltransferase complex from Saccharomyces cerevisiae. Isolation of the OST6 gene, its synthetic interaction with OST3, and analysis of the native complex.Semantic proximity Read ↗

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STT3, a highly conserved protein required for yeast oligosaccharyl transferase activity in vivo.Semantic proximity Read ↗

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