Article
A quorum-sensing regulator controls expression of both the type IV secretion system and the flagellar apparatus of Brucella melitensis.
Cellular microbiology - 1 Aug 2005
Delrue Rose-May, Deschamps Chantal, Léonard Sandrine, Nijskens Caroline, Danese Isabelle, Schaus Jean-Michel, Bonnot Sophie, Ferooz Jonathan, Tibor Anne, De Bolle Xavier, Letesson Jean-Jacques
Abstract excerpt
Both a type IV secretion system and a flagellum have been described in Brucella melitensis. These two multimolecular surface appendages share several features. Their expression in bacteriological medium is growth curve dependent, both are induced intracellularly and are required for full virulence in a mouse model of infection. Here we report the identification of VjbR, a quorum sensing-related transcriptional...
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