Article
The sheathed flagellum of Brucella melitensis is involved in persistence in a murine model of infection.
Cellular microbiology - 1 May 2005
Fretin D, Fauconnier A, Köhler S, Halling S, Léonard S, Nijskens C, Ferooz J, Lestrate P, Delrue R-M, Danese I, Vandenhaute J, Tibor A, DeBolle X, Letesson J-J
Abstract excerpt
Persistence infection is the keystone of the ruminant and human diseases called brucellosis and Malta fever, respectively, and is linked to the intracellular tropism of Brucella spp. While described as non-motile, Brucella spp. have all the genes except the chemotactic system, necessary to assemble a functional flagellum. We undertook to determine whether these genes are expressed and are playing a role in some...
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