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Article

Identification of a new virulence factor, BvfA, in Brucella suis.

Infection and immunity - 1 Sept 2005

Lavigne Jean-Philippe, Patey Gilles, Sangari Felix J, Bourg Gisèle, Ramuz Michel, O'Callaghan David, Michaux-Charachon Sylvie

Abstract excerpt

We report the identification of BvfA (for Brucella virulence factor A), a small periplasmic protein unique to the genus Brucella, which is essential for the virulence of Brucella suis. A BvfA knockout mutant was highly attenuated both in in vitro macrophage infection assays and in vivo in the murine model of brucellosis. Fluorescence-activated cell sorting analysis with green fluorescent protein fusions showed...

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PMID: 16113268
DOI: 10.1128/IAI.73.9.5524-5529.2005
PMCID: PMC1231096

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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