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Article

Interleukin-6 polymorphism is associated with more aggressive prostate cancer.

The Journal of urology - 1 Aug 2005

Tan Dongfeng, Wu Xiuxian, Hou Min, Lee Soo Ok, Lou Wei, Wang Jianmin, Janarthan Bagirathan, Nallapareddy Sujatha, Trump Donald L, Gao Allen C

Abstract excerpt

PURPOSE: : Interleukin-6 (IL-6) has an important role during prostate cancer progression and IL-6 levels in the serum of patients with hormone refractory and metastatic prostate cancer are significantly increased compared with those in patients with hormone sensitive and localized prostate cancer. The G>C polymorphism at position -174 in the promoter of the IL-6 gene has been associated with differences in IL-6...

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Source

Identifiers

PMID: 16006970
DOI: 10.1097/01.ju.0000168723.42824.40

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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