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Article

Serotonin 2c receptor RNA editing in major depression and suicide

9 Mar 2012

Abstract excerpt

OBJECTIVES: mRNA for serotonin 2C receptor (5-HT(2C)R) undergoes editing which results in numerous isoforms. More highly edited isoforms exhibit decreased function. We recently found greater 5-HT(2C)R editing in suicide victims with prior bipolar disorder (BPD) or schizophrenia (SZ) compared with non-suicide patients and normal controls (NC). This study compares suicides and non-suicides with major depressive...

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Identifiers

PMID: 22404657
DOI: 10.3109/15622975.2011.630406

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