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Article

Lack of association with the CD28/CTLA4/ICOS gene region among Norwegian multiple sclerosis patients.

Journal of neuroimmunology - 1 Sept 2005

Lorentzen Aslaug R, Celius Elisabeth G, Ekstrøm Per O, Wiencke Kristine, Lie Benedicte A, Myhr Kjell-Morten, Ling Vincent, Thorsby Erik, Vartdal Frode, Spurkland Anne, Harbo Hanne F

Abstract excerpt

Chromosome region 2q33 encodes several regulators of the immune system, among these the CD28, CTLA4, and ICOS molecules. Involvement of these genes in multiple sclerosis (MS) is not yet clear. We investigated six microsatellites and three SNPs in a relatively large and clinically well characterised Norwegian MS cohort. No associations were observed for any of the markers analysed in 575 MS patients and 551...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 16005527
DOI: 10.1016/j.jneuroim.2005.06.002

Genes

CTLA4
ICOS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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