Article
No major effect of the CD28/CTLA4/ICOS gene region on susceptibility to primary sclerosing cholangitis.
Scandinavian journal of gastroenterology - 1 May 2006
Wiencke Kristine, Boberg Kirsten Muri, Donaldson Peter, Harbo Hanne, Ling Vincent, Schrumpf Erik, Spurkland Anne
Abstract excerpt
OBJECTIVE: Primary sclerosing cholangitis (PSC) is currently thought to be an immune-mediated disease, where both host genes and environmental factors interact. Some of the immunoregulatory genes responsible for individual susceptibility to PSC have been identified. The co-stimulatory receptor ge...
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