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Article

RIG1 inhibits the Ras/mitogen-activated protein kinase pathway by suppressing the activation of Ras.

Cellular signalling - 1 Mar 2006

Tsai Fu-Ming, Shyu Rong-Yaun, Jiang Shun-Yuan

Abstract excerpt

The retinoid-inducible gene 1 (RIG1) protein is a retinoid-inducible growth regulator. Previous studies have shown that the RIG1 protein inhibits the signaling pathways of Ras/mitogen-activated protein kinases. However, neither the mode of action nor the site of inhibition of RIG1 is known. This study investigated the effects of RIG1, and the mechanisms responsible for these effects, on the activation of Ras...

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Identifiers

PMID: 16005186
DOI: 10.1016/j.cellsig.2005.05.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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