Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Expression of GRIM-19 in unexplained recurrent spontaneous abortion and possible pathogenesis.

Molecular human reproduction - 1 Jul 2018

Yang Yang, Cheng Laiyang, Deng Xiaohui, Yu Hongling, Chao Lan

Abstract excerpt

STUDY QUESTION: Is aberrant expression of gene associated with retinoid-interferon-induced mortality-19 (GRIM-19) associated with unexplained recurrent spontaneous abortion (URSA)? SUMMARY ANSWER: GRIM-19 deficiency may regulate regulatory T cell/T helper 17 cell (Treg/Th17) balance partly through reactive oxygen species (ROS)-mammalian target of rapamycin (mTOR) signaling axis in URSA. WHAT IS KNOWN ALREADY:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Abortion, Habitual
Share to Immune Tolerance
Share to Jurkat Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lymphocyte Count

Share to NADH, NADPH Oxidoreductases

Share to Parity

Share to Th17 Cells

Share to TOR Serine-Threonine Kinases

Source

Identifiers

PMID: 29741731
DOI: 10.1093/molehr/gay020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of GRIM-19 in unexplained recurrent spontaneous abortion and possible pathogenesis.PMID 29741731Read ↗

Key Gene and Functional Pathways Identified in Unexplained Recurrent Spontaneous Abortion Using Targeted RNA Sequencing and Clinical AnalysisSemantic proximity Read ↗

The effect and mechanism of Grim 19 on mouse sperm quality and testosterone synthesisSemantic proximity Read ↗

GRIM-19 deficiency promotes macrophage polarization to the M1 phenotype partly through glycolysis in unexplained recurrent spontaneous abortion†.Semantic proximity Read ↗

Differences in Cytokine Expression and STAT3 Activation between Healthy Controls and Patients of Unexplained Recurrent Spontaneous Abortion (URSA) during Early PregnancySemantic proximity Read ↗

A SNP in pri-miR-10a is associated with recurrent spontaneous abortion in a Han-Chinese population.Semantic proximity Read ↗

AMPK-mTOR pathway modulates glycolysis reprogramming in unexplained recurrent spontaneous abortionSemantic proximity Read ↗

The Regulatory Role of Decidual RHOQ Downregulation on Aberrant Dendritic Cell Activation in Recurrent MiscarriageSemantic proximity Read ↗

Dysregulation of microRNAs and their associations with clinical characteristics in recurrent spontaneous abortion patientsSemantic proximity Read ↗

Tumor-Suppressive Activity of the Cell Death Activator GRIM-19 on a Constitutively Active Signal Transducer and Activator of Transcription 3Semantic proximity Read ↗

Association of miR-34a-3p/5p, miR-141-3p/5p, and miR-24 in Decidual Natural Killer Cells with Unexplained Recurrent Spontaneous AbortionSemantic proximity Read ↗

Correlation of TGF-β signaling pathway gene polymorphisms with unexplained recurrent spontaneous abortion.Semantic proximity Read ↗

Study on the immunomodulatory mechanism of vitamin D in patients with unexplained recurrent spontaneous abortionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.