Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Rapid genotyping of the OATP1B1 polymorphisms A388G and T521C with real-time PCR FRET assays.

Pharmacogenomics - 1 Jun 2005

Op den Buijsch Robert A M, Wijnen Petal A H M, van Dieijen-Visser Marja P, de Vries Johan E, Bekers Otto

Abstract excerpt

The polymorphisms (OATP)1B1 A388G and T521C of the solute carrier organic anion-transporter family member 1B1 gene (SLCO1B1), previously known as OATP-C, have potential impacts on drug metabolism. In order to establish a fast and consistent assay for these polymorphisms, rapid speed polymerase chain reaction (PCR) fluorescence resonance energy transfer (FRET) assays on the LightCycler were developed for both...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Alleles
Share to DNA

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescence Resonance Energy Transfer

Share to Liver-Specific Organic Anion Transporter 1

Share to Organic Anion Transporters

Share to Polymorphism, Restriction Fragment Length

Share to Reverse Transcriptase Polymerase Chain Reaction

Source

Identifiers

PMID: 16004557
DOI: 10.1517/14622416.6.4.393

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Rapid genotyping of the OATP1B1 polymorphisms A388G and T521C with real-time PCR FRET assays.PMID 16004557Read ↗

Frequency of the SLCO1B1 388A>G and the 521T>C polymorphism in Tanzania genotyped by a new LightCycler®-based method.Semantic proximity Read ↗

Direct and rapid genotyping of SLCO1B1 388A>G and 521T>C in human blood specimens using the SmartAmp-2 method.Semantic proximity Read ↗

Allele-specific real-time polymerase chain reaction as a tool for urate transporter 1 mutation detection.Semantic proximity Read ↗

Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing.Semantic proximity Read ↗

Simple and rapid detection method for the mutations in SLC22A12 that cause hypouricemia by allele-specific real-time polymerase chain reaction.Semantic proximity Read ↗

Rapid Detection of SLCO1B1 Polymorphisms Using Duplex Fluorescence Melting Curve Analysis: Implications for Personalized Drug Dosing in Clinical Settings.Semantic proximity Read ↗

A fast SSP-PCR method for genotyping the ATP-binding cassette subfamily B member 1 gene C3435T and G2677T polymorphisms in Chinese transplant recipients.Semantic proximity Read ↗

SLCO1B1 c.521T>C Genotyping in the Austrian Population Using 2 Commercial Real-Time Polymerase Chain Reaction Assays: An Implementation Study.Semantic proximity Read ↗

Realtime exonuclease-mediated allelic discrimination (READ): a simple homogeneous genotyping assay for SNPs at the ABC gene loci.Semantic proximity Read ↗

Frequencies of single-nucleotide polymorphisms of SLCO1A2, SLCO1B3 and SLCO2B1 genes in a Finnish population.Semantic proximity Read ↗

Genotyping of the PXR A11156C polymorphism with locked nucleic acid containing fluorogenic probes.Semantic proximity Read ↗

Maraviroc is a substrate for OATP1B1 in vitro and maraviroc plasma concentrations are influenced by SLCO1B1 521 T>C polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.