Article
Genetic analysis of the larval optic nerve projection in Drosophila.
Development (Cambridge, England) - 1 Mar 1997
Schmucker D, Jäckle H, Gaul U
Abstract excerpt
The Drosophila larval optic nerve, called Bolwig's nerve (BN), projects into the central brain along a simple invariant path. The growth of the BN proceeds in three phases, during which the nerve changes direction at two intermediate targets, P1 and P2. Here we show that the projection of the BN is amenable to genetic dissection. In a mutagenesis screen, we have isolated mutations in 13 genes that disrupt the BN...
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