Article
Association of HLA-E Polymorphism with Severe Bacterial Infection and Early Transplant-Related Mortality in Matched Unrelated Bone Marrow Transplantation
6 Jul 2005
Abstract excerpt
Despite prophylactic measures, susceptibility to severe infections in patients who had undergone bone marrow transplantation (BMT) is quite variable. To evaluate the potential role of human leukocyte antigen (HLA)-E polymorphism on the incidence of early infections, we analyzed 77 unrelated-donor (UD) BMT pairs identically matched for classical HLA class I and class II alleles. Multivariate analysis taking into...
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