Article
CARD15/NOD2 polymorphisms do not explain concordance of Crohn's disease in Swedish monozygotic twins.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Oct 2005
Halfvarson J, Bresso F, D'Amato M, Järnerot G, Pettersson S, Tysk C
Abstract excerpt
BACKGROUND: CARD15/NOD2 polymorphisms are associated with Crohn's disease. There is a high concordance for disease and disease phenotype in monozygotic twin pairs with Crohn's disease. AIM: We studied CARD15/NOD2 polymorphisms in a Swedish, population-based cohort of monozygotic twins with Crohn's disease to assess whether these variants explain disease concordance. SUBJECTS AND METHODS: Twenty-nine monozygotic...
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