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Article

Genetic and environmental factors in monozygotic twins with Crohn's disease and their first-degree relatives: a case report.

Digestion - 1 Jan 2005

Vind Ida, Jespersgaard Cathrine, Hougs Lotte, Riis Lene, Dinesen Lotte, Andersen Paal Skytt, Locht Henning, Jess Tine, Munkholm Pia

Abstract excerpt

BACKGROUND/AIMS: Familial Crohn's disease has shown concordance concerning location and clinical type of the disease especially among monozygotic twins. Susceptibility to Crohn's disease is both based on genetic and environmental factors. We investigated polymorphisms of CARD15, TLR4, and OCTN, and environmental factors in a monozygotic twin pair with Crohn's disease and their first-degree relatives. METHODS:...

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Source

Identifiers

PMID: 16024933
DOI: 10.1159/000087053

Genes

TLR4

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