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Article

Use of a locked-nucleic-acid oligomer in the clamped-probe assay for detection of a minority Pfcrt K76T mutant population of Plasmodium falciparum.

Journal of clinical microbiology - 1 Jul 2005

Senescau Alice, Berry Antoine, Benoit-Vical Françoise, Landt Olfert, Fabre Richard, Lelièvre Joël, Cassaing Sophie, Magnaval Jean-François

Abstract excerpt

Given the emergence of drug resistance and the high rate of polyclonal microorganism infections, the availability of a fast and sensitive test to detect minority mutant populations would be an improvement in the diagnosis of infectious diseases. A clamped-probe real-time PCR assay to diagnose the Plasmodium falciparum K76T mutation in clone populations was developed, using a wild-type-specific...

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Identifiers

PMID: 16000452
DOI: 10.1128/JCM.43.7.3304-3308.2005
PMCID: PMC1169138

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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