Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytes

5 Jul 2005

Abstract excerpt

T lymphocytes and a subpopulation of B lymphocytes express the CD5 coreceptor. Its functional importance is evident from the multiple levels and developmental stages of the regulation of its expression. We here report the discovery of a novel regulatory exon upstream of the noncoding region of the CD5 gene in humans. This alternate exon 1 is designated E1B (with the conventional exon 1 renamed E1A) and was shown...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chronic Lymphocytic Leukemia Research
Share to Immune Cell Function and Interaction
Share to T-cell and B-cell Immunology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15998834
DOI: 10.1182/blood-2005-02-0597

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytesPMID 15998834Read ↗

Genomic organization of the human CD5 geneSemantic proximity Read ↗

CD5 Expression in B Cells from Patients with Systemic Lupus ErythematosusSemantic proximity Read ↗

Natural phosphorylation of CD5 in chronic lymphocytic leukemia B cells and analysis of CD5-regulated genes in a B cell line suggest a role for CD5 in malignant phenotype.Semantic proximity Read ↗

The structure of human STAT5A and B genes reveals two regions of nearly identical sequence and an alternative tissue specific STAT5B promoterSemantic proximity Read ↗

HIF-1α regulates the expression of the non-conventional isoform of the cd5 gene in T cells under the hypoxic condition: A potential mechanism for CD5neg/low phenotype of infiltrating cells in solid tumors.Semantic proximity Read ↗

Transduction of the human gene FAM8A1 by endogenous retrovirus during primate evolution.Semantic proximity Read ↗

E26 transformation-specific transcription variant 5 in development and cancer: modification, regulation and functionSemantic proximity Read ↗

ENTPD5: identification of splicing variants and their impact on cancer survival.Semantic proximity Read ↗

Evolutionary and functional evidence for positive selection at the human CD5 immune receptor gene.Semantic proximity Read ↗

The ancient fusogen EnvP(b)1 is expressed in human tissues and its structure informs the evolution of gammaretrovirus envelope proteinsSemantic proximity Read ↗

Genomic Mutations of the STAT5 Transcription Factor Are Associated with Human Cancer and Immune Diseases.Semantic proximity Read ↗

CD5 Promotes IL-10 Production in Chronic Lymphocytic Leukemia B Cells through STAT3 and NFAT2 ActivationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.