Article
Evolutionary and functional evidence for positive selection at the human CD5 immune receptor gene.
Molecular biology and evolution - 1 Feb 2012
Carnero-Montoro Elena, Bonet Lizette, Engelken Johannes, Bielig Torsten, Martínez-Florensa Mario, Lozano Francisco, Bosch Elena
Abstract excerpt
CD5 is a lymphocyte surface coreceptor of still incompletely understood function. Currently available information indicates that CD5 participates not only in cell-to-cell immune interactions through still poorly defined endogenous ligands expressed on hemopoietic and nonhemopoietic cells but also in recognition of exogenous and highly conserved microbial structures such as fungal β-glucans. Preceding single...
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