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Article

High prevalence and possible de novo formation of BRAF mutation in metastasized papillary thyroid cancer in lymph nodes.

The Journal of clinical endocrinology and metabolism - 1 Sept 2005

Vasko Vasily, Hu Shuiying, Wu Guojun, Xing Jeffrey C, Larin Alexandr, Savchenko Victoria, Trink Barry, Xing Mingzhao

Abstract excerpt

CONTEXT: The role of the T1799A BRAF mutation in lymph node metastasis of papillary thyroid cancer (PTC) is not clear. OBJECTIVE: Our objective was to explore the relationship between BRAF mutation and lymph node metastasis of PTC by examining the mutation in both the primary tumors and their paired lymph node metastases. DESIGN: We isolated genomic DNA from primary thyroid tumors and paired lymph node metastases...

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Source

Identifiers

PMID: 15998781
DOI: 10.1210/jc.2004-2353

Genes

BRAF
GAA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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