Article
Genetic and genomic studies of PADI4 in rheumatoid arthritis.
Rheumatology (Oxford, England) - 1 Jul 2005
Harney S M J, Meisel C, Sims A-M, Woon P Y, Wordsworth B P, Brown M A
Abstract excerpt
OBJECTIVES: Strong genetic association of rheumatoid arthritis (RA) with PADI4 (peptidyl arginine deiminase) has previously been described in Japanese, although this was not confirmed in a subsequent study in the UK. We therefore undertook a further study of genetic association between PADI4 and RA in UK Caucasians and also studied expression of PADI4 in the peripheral blood of patients with RA. METHODS: Seven...
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