Article
PADI4 genotype is not associated with rheumatoid arthritis in a large UK Caucasian population.
Annals of the rheumatic diseases - 1 Apr 2010
Burr Marian L, Naseem Haris, Hinks Anne, Eyre Steve, Gibbons Laura J, Bowes John, Wilson Anthony G, Maxwell James, Morgan Ann W, Emery Paul, Steer Sophia, Hocking Lynne, Reid David M, Wordsworth Paul, Harrison Pille, Thomson Wendy, Worthington Jane, Barton Anne
Abstract excerpt
BACKGROUND: Polymorphisms of the peptidylarginine deiminase type 4 (PADI4) gene confer susceptibility to rheumatoid arthritis (RA) in East Asian people. However, studies in European populations have produced conflicting results. This study explored the association of the PADI4 genotype with RA in a large UK Caucasian population. METHODS: The PADI4_94 (rs2240340) single nucleotide polymorphism (SNP) was directly...
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