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Article

NF-kappaB, Nrf2, and HO-1 interplay in redox-regulated VCAM-1 expression.

Antioxidants & redox signaling - 1 Jan 2000

Banning Antje, Brigelius-Flohé Regina

Abstract excerpt

Oxidative processes are considered to play a crucial role in the induction of cell adhesion molecules, a key event in inflammatory processes. We recently reported on an unexpected unidirectional effect of an overexpressed antioxidant [phospholipid hydroperoxide glutathione peroxidase (PHGPx)] and an oxidant [15-lipoxygenase (15-LOX)] enzyme on the basal and interleukin-1 induced vascular cell adhesion molecule-1...

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Source

Identifiers

PMID: 15998244
DOI: 10.1089/ars.2005.7.889

Genes

LOX

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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