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Article

Expression of heme oxygenase-1 in human livers before transplantation correlates with graft injury and function after transplantation.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons - 1 Aug 2005

Geuken Erwin, Buis Carlijn I, Visser Dorien S, Blokzijl Hans, Moshage Han, Nemes Balazs, Leuvenink Henri G D, de Jong Koert P, Peeters Paul M J G, Slooff Maarten J H, Porte Robert J

Abstract excerpt

Upregulation of heme oxygenase-1 (HO-1) has been proposed as an adaptive mechanism protecting against ischemia/reperfusion (I/R) injury. We investigated HO-1 expression in 38 human liver transplants and correlated this with I/R injury and graft function. Before transplantation, median HO-1 mRNA levels were 3.4-fold higher (range: 0.7-9.3) in donors than in normal controls. Based on the median value, livers were...

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Identifiers

PMID: 15996234
DOI: 10.1111/j.1600-6143.2005.00960.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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