Article
Global gene expression profiling unveils S100A8/A9 as candidate markers in H-ras-mediated human breast epithelial cell invasion.
Molecular cancer research : MCR - 1 Oct 2008
Moon Aree, Yong Hae-Young, Song Jae-In, Cukovic Daniela, Salagrama Sridevi, Kaplan David, Putt David, Kim Hyesook, Dombkowski Alan, Kim Hyeong-Reh Choi
Abstract excerpt
The goal of the present study is to unveil the gene expression profile specific to the biological processes of human breast epithelial cell invasion and migration using an MCF10A model genetically engineered to constitutively activate the H-ras or N-ras signaling pathway. We previously showed that H-Ras, but not N-Ras, induces MCF10A cell invasion/migration, whereas both H-Ras and N-Ras induce cell proliferation...
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