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Article

Heritable and inducible gene knockdown in C. elegans using Wormgate and the ORFeome.

Gene - 10 Oct 2005

Johnson Nicholas M, Behm Carolyn A, Trowell Stephen C

Abstract excerpt

Double-stranded RNA (dsRNA) mediated gene silencing (RNA interference; RNAi) is a powerful tool for investigating gene function. It is usually performed in Caenorhabditis elegans via the injection or oral delivery of dsRNA, but an alternative approach, the expression of RNA hairpins from introduced DNA (hairpin RNAi; hpRNAi) has several advantages: (1) it can be induced systemically or in a tissue-specific...

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PMID: 15994029
DOI: 10.1016/j.gene.2005.05.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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