Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivoLPS infusion study

10 Aug 2011

Abstract excerpt

BACKGROUND: It is widely accepted that atherosclerosis and inflammation are intimately linked. Monocytes play a key role in both of these processes and we hypothesized that activation of inflammatory pathways in monocytes would lead to, among others, proatherogenic changes in the monocyte transcriptome. Such differentially expressed genes in circulating monocytes would be strong candidates for further...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipokines, Inflammation, and Metabolic Diseases
Share to Atherosclerosis and Cardiovascular Diseases
Share to Immune Response and Inflammation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 21827714
DOI: 10.1186/1755-8794-4-64

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of candidate genes linking systemic inflammation to atherosclerosis; results of a human in vivoLPS infusion studyPMID 21827714Read ↗

Gene Profiling of Human Adipose Tissue During Evoked Inflammation In VivoSemantic proximity Read ↗

Identification of High and Low Responders to Lipopolysaccharide in Normal Subjects: An Unbiased Approach to Identify Modulators of Innate ImmunitySemantic proximity Read ↗

Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and candidate biomarkersSemantic proximity Read ↗

The Acute Effects of Lipoprotein Apheresis on Monocyte Subset Distribution and Transcriptome in Patients With and Without Elevated Lipoprotein(a)Semantic proximity Read ↗

Acute hyperlipidemia initiates proinflammatory and proatherogenic changes in circulation and adipose tissue in obese women.Semantic proximity Read ↗

Priming of human monocytes by β-glucan and obesity-associated factors: modifications to global DNA methylation, gene expression, phenotype and function.Semantic proximity Read ↗

Hypertension and increased endothelial mechanical stretch promote monocyte differentiation and activation: roles of STAT3, interleukin 6 and hydrogen peroxide.Semantic proximity Read ↗

Genetic determinants of cytokine production in activated human monocytesSemantic proximity Read ↗

Lipoprotein (a) up-regulates the expression of the plasminogen activator inhibitor 2 in human blood monocytes.Semantic proximity Read ↗

Monocytes as a diagnostic marker of cardiovascular diseases.Semantic proximity Read ↗

Expression profiling of macrophages from subjects with atherosclerosis to identify novel susceptibility genes.Semantic proximity Read ↗

Application of leukocyte transcriptomes to assess systemic consequences of risk factors for cardiovascular disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.