Article
Characterization of the promoter of human extracellular matrix metalloproteinase inducer (EMMPRIN).
Gene - 9 Jan 2002
Liang Liang, Major Terry, Bocan Thomas
Abstract excerpt
Monocyte-derived macrophages play a central role in atherosclerotic lesion formation and potentially plaque destabilization by expression of matrix metalloproteinases (MMPs); however, mechanisms associated with stimulating MMP production are not clearly understood. EMMPRIN, which is expressed by human cancer cells and macrophages, present in human, mouse and rabbit atherosclerosis and noted to induce MMPs may be...
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