Article
Novel substitution polymorphisms of human immunoglobulin VH genes in Mexicans.
Human immunology - 1 Jun 2005
Romo-González Tania, Morales-Montor Jorge, Rodríguez-Dorantes Mauricio, Vargas-Madrazo Enrique
Abstract excerpt
It has been proposed that the defense and recognition functions of the immune system, especially those mediated by antibodies, require a great diversity of receptors. Nonetheless, functional and structural evidence has demonstrated the presence of restrictions, both in the use of the repertoire and in the recognition of antigens. Fifty-one functional genes have been described in the IghV locus; however, there is...
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