Article
SYNGR1 is associated with schizophrenia and bipolar disorder in southern India.
Journal of human genetics - 1 Jan 2005
Verma Ranjana, Kubendran Shobana, Das Swapan Kumar, Jain Sanjeev, Brahmachari Samir K
Abstract excerpt
Chromosome 22q11-13 is one of the most consistent linkage regions for schizophrenia (SCZ) and bipolar disorder (BPAD). The SYNGR1 gene, which is associated with presynaptic vesicles in neuronal cells, is located on 22q13.1. We have previously identified a novel nonsense mutation in the SYNGR1 gene in a SCZ pedigree. In the present study, a detailed analysis of this gene was performed in a case-control cohort (198...
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