Article
Simultaneous determination of single nucleotide polymorphisms of MDR1 genes by electrochemical DNA chip.
Drug metabolism and pharmacokinetics - 1 Jun 2005
Nakamura Tsutomu, Sakaeda Toshiyuki, Takahashi Masayoshi, Hashimoto Koji, Gemma Nobuhiro, Moriya Yuka, Komoto Chiho, Nishiguchi Kohshi, Okamura Noboru, Okumura Katsuhiko
Abstract excerpt
The on-chip genotyping system ("the electrochemical DNA chip") has been developed as a more cost-effective genotyping system and was applied to MDR1 genotyping in the present study, which is required for wide use in clinical application and for personalized medication based on genotype. The electrochemical DNA chip was optimized and applied to simultaneous genotyping of four MDR1 polymorphisms (T-129C, C1236T,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
