Article
Construction of an electrochemical DNA chip for simultaneous genotyping of single nucleotide polymorphisms.
The Analyst - 1 May 2005
Takahashi Masayoshi, Okada Jun, Ito Keiko, Hashimoto Michie, Hashimoto Koji, Yoshida Yuri, Furuichi Yasuhiro, Ohta Yasuhiko, Mishiro Sunji, Gemma Nobuhiro
Abstract excerpt
An electrochemical DNA chip was constructed for simultaneous genotyping of single nucleotide polymorphisms (SNPs) using genomic DNA extracted from blood samples. This chip consisted of electrodes located on a single piece of substrate and allele-specific oligonucleotide probes on the electrodes. As a first application, the 4 SNPs (MxA[-88], MxA[-123], MBL[X/Y], and MBL[A/B]), which have association with the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
