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Article

Energy metabolism in heart failure and remodelling.

Cardiovascular research - 15 Feb 2009

Ingwall Joanne S

Abstract excerpt

Myocytes of the failing heart undergo impressive metabolic remodelling. The time line for changes in the pathways for ATP synthesis in compensated hypertrophy is: flux through the creatine kinase (CK) reaction falls as both creatine concentration ([Cr]) and CK activity fall; increases in [ADP] and [AMP] lead to increases in glucose uptake and utilization; fatty acid oxidation either remains the same or decreases....

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cardiomyopathy, Hypertrophic, Familial

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Share to Mitochondria, Heart

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Source

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Identifiers

PMID: 18987051
DOI: 10.1093/cvr/cvn301
PMCID: PMC2639129

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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