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Article

Electrokinetically based approach for single-nucleotide polymorphism discrimination using a microfluidic device.

Analytical chemistry - 1 Jul 2005

Erickson David, Liu Xuezhu, Venditti Roberto, Li Dongqing, Krull Ulrich J

Abstract excerpt

In this work, we describe and implement an electrokinetic approach for single-nucleotide polymorphism (SNP) discrimination using a PDMS/glass-based microfluidic chip. The technique takes advantage of precise control of the coupled thermal (Joule heating), shear (electroosmosis), and electrical (electrophoresis) energies present at an array of probes afforded by the application of external electrical potentials....

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Source

Identifiers

PMID: 15987103
DOI: 10.1021/ac050236r

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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