Article
Upstream transcription factor-1 gene polymorphism is associated with increased adipocyte lipolysis.
The Journal of clinical endocrinology and metabolism - 1 Sept 2005
Hoffstedt Johan, Rydén Mikael, Wahrenberg Hans, van Harmelen Vanessa, Arner Peter
Abstract excerpt
OBJECTIVE: Variations in lipid metabolism between individuals could be due to genetic factors. A transmission of a haplotype of the upstream transcription factor-1 (USF-1) gene containing the minor alleles at the usf1s1 and usfs2 loci is described. We investigated whether these polymorphisms are associated with adipocyte lipolysis. METHODS AND RESULTS: A total of 196 healthy obese women were investigated for in...
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