Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressors

24 Jun 2005

Abstract excerpt

Limited information is available on the molecular mechanisms by which long-term HIV-1-infected nonprogressors suppress HIV-1 infection and maintain immune functions. The intestinal mucosal immune system is an early target for HIV-1 infection and severe CD4+ T cell depletion. We evaluated mucosal T lymphocyte subsets, virus-specific cellular responses, gene expression profiles, and viral loads in intestinal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to HIV/AIDS Research and Interventions
Share to HIV-related health complications and treatments
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15980151
DOI: 10.1073/pnas.0503463102

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gut mucosal T cell responses and gene expression correlate with protection against disease in long-term HIV-1-infected nonprogressorsPMID 15980151Read ↗

The Gut Mucosal Viral Reservoir in HIV-Infected Patients Is Not the Major Source of Rebound Plasma Viremia following Interruption of Highly Active Antiretroviral TherapySemantic proximity Read ↗

Early Antiretroviral Therapy for Simian Immunodeficiency Virus Infection Leads to Mucosal CD4<sup>+</sup>T-Cell Restoration and Enhanced Gene Expression Regulating Mucosal Repair and RegenerationSemantic proximity Read ↗

The Hitchhiker Guide to CD4+ T-Cell Depletion in Lentiviral Infection. A Critical Review of the Dynamics of the CD4+ T Cells in SIV and HIV Infection.Semantic proximity Read ↗

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and MortalitySemantic proximity Read ↗

Endogenous Retroelement Expression in the Gut Microenvironment of People Living with HIV-1Semantic proximity Read ↗

Correlating cellular and molecular signatures of mucosal immunity that distinguish HIV controllers from noncontrollersSemantic proximity Read ↗

Host genetic and immune factors drive evasion of HIV-1 pathogenesis in viremic non-progressors.Semantic proximity Read ↗

Compartmentalized Human Immunodeficiency Virus Type 1 Reservoir in Intestinal Monocytes/Macrophages on Antiretroviral TherapySemantic proximity Read ↗

Immune dysregulation and CD4+ T cell loss in HIV-1 infection.Semantic proximity Read ↗

Intact proviruses are enriched in the colon and associated with PD-1+TIGIT− mucosal CD4+ T cells of people with HIV-1 on antiretroviral therapySemantic proximity Read ↗

Single-cell profiling of environmental enteropathy reveals signatures of epithelial remodeling and immune activation in severe diseaseSemantic proximity Read ↗

Omic Technologies in HIV: Searching Transcriptional Signatures Involved in Long-Term Non-Progressor and HIV Controller Phenotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.