Article
Yeast aconitase in two locations and two metabolic pathways: seeing small amounts is believing.
Molecular biology of the cell - 1 Sept 2005
Regev-Rudzki Neta, Karniely Sharon, Ben-Haim Nitzan Natani, Pines Ophry
Abstract excerpt
The distribution of identical enzymatic activities between different subcellular compartments is a fundamental process of living cells. At present, the Saccharomyces cerevisiae aconitase enzyme has been detected only in mitochondria, where it functions in the tricarboxylic acid (TCA) cycle and is considered a mitochondrial matrix marker. We developed two strategies for physical and functional detection of...
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