Article
Phenotype analysis using network motifs derived from changes in regulatory network dynamics.
Proteins - 15 Aug 2005
Cavelier German, Anastassiou Dimitris
Abstract excerpt
The intrinsic dynamic response of a transcriptional regulatory network depends directly on molecular interactions in the cellular transcription, translation, and degradation machineries. These interactions can be incorporated into dynamic mathematical models of the biochemical system using the biophysical relationship with the model parameters. Modifications of such interactions bring changes to the biological...
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