Article
Inferring gene networks from steady-state response to single-gene perturbations.
Journal of theoretical biology - 21 Dec 2005
Brazhnik Paul
Abstract excerpt
Inferring gene networks from gene expression data is an important step in understanding the molecular machinery of life. Three methods for establishing and quantifying causal relationships between genes based on steady-state measurements in single-gene perturbation experiments have recently been proposed: the regulatory strength method, the local regulatory strength method, and Gardner's method. The theoretical...
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