Article
HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites.
Breast cancer research and treatment - 1 Jun 2003
Millikan Robert, Eaton Allison, Worley Kendra, Biscocho Lorna, Hodgson Elizabeth, Huang Wen-Yi, Geradts Joseph, Iacocca Mary, Cowan David, Conway Kathleen, Dressler Lynn
Abstract excerpt
BACKGROUND: Several recent epidemiologic studies examined the association between breast cancer risk and an inherited, single-nucleotide polymorphism in the HER2 gene, codon 655 G to A, which leads to an amino acid substitution of Ile to Val. Results of previous studies have been mixed, with most studies showing no association but some suggesting an association in younger women or women with a family history of...
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