Article
HER2 Codon 655 (Ile/Val) Polymorphism and Breast Cancer in Austrian Women.
Anticancer research - 1 Dec 2015
Watrowski Rafał, Castillo-Tong Dan Cacsire, Wolf Andrea, Schuster Eva, Fischer Michael B, Speiser Paul, Zeillinger Robert
Abstract excerpt
BACKGROUND: The overexpression of the human epidermal growth factor receptor 2 (HER2) in breast cancer (BC) is associated with impaired prognosis. Data concerning the HER2 codon 655 polymorphism (Ile/Val) and BC risk are conflicting. MATERIALS AND METHODS: We studied the HER2 codon 655 (rs1136201) polymorphism in 80 Austrian patients with BC and 100 healthy volunteers by pyrosequencing and polymerase chain...
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